A targeted approach for patient assessment is provided and applied to each scenario, showing how to rapidly identify important clues to distinguish among common diagnoses, including both benign and malignant causes of pain.

Tools for implementing both medication and non-medication therapies, such as exercise and relaxation techniques, are also included.Įach chapter opens with typical presentations of three to five common patient scenarios, including pediatric, adult, and geriatric patients. Offering strategies for rapidly evaluating and treating pain complaints by body region, this innovative title also provides patient educational handouts that explain the diagnosis and treatment in easy-to-understand language for each condition.

Headache and Chronic Pain Syndromes provides a case-based approach to state-of-the-art evaluation and treatment of patients with common chronically painful conditions. Chapters have been contributed by internationally recognized leaders in the field of IgA research, representing 8 countries on 3 continents. This book is designed to serve as a concise reference of the present knowledge of the biology of IgA, including structure of IgA and its interaction with Fc receptors epithelial transport of IgA regulation of the mucosal IgA system biological roles of IgA, including newly discovered functions IgA-associated diseases, and therapeutic applications for IgA. Recent advances in human genomics, gene regulation, structural biology, cell signaling, and immunobiology have greatly enhanced our understanding of this important class of antibody. IgA is the second most abundant class of antibody in the bloodstream, contributing to systemic as well as secretory immunity. It has been estimated that more than 3 grams of IgA are transported daily into mucosal secretions, carrying out a wide range of antimicrobial and anti-inflammatory functions. Humans produce more immunoglobulin A (IgA) than all other antibody isotypes combined, most of which is rapidly transported into the external secretions bathing mucous membranes. This volume draws on a broad spectrum of molecular biologic, biochemical, and immunogenetic approaches in combination with human and murine in vitro cell culture and in vivo model systems to address questions in mucosal immunity.

Publisher: Springer | Language: English |ĭescription: Immune responses at mucosal surfaces play a major role in host mucosal defense against microbial pathogens and in the pathogenesis of acute and chronic mucosal inflammatory diseases.

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